|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:coenzyme
|
|
gptkbp:abbreviation
|
gptkb:BH4
|
|
gptkbp:alternativeName
|
gptkb:BH4
sapropterin
tetrahydropterin
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:associatedWith
|
gptkb:phenylketonuria
dopa-responsive dystonia
hyperphenylalaninemia
tetrahydrobiopterin deficiency
|
|
gptkbp:biosynthesized_from
|
gptkb:GTP
|
|
gptkbp:CASNumber
|
17528-96-8
|
|
gptkbp:charge
|
neutral
|
|
gptkbp:chemicalFormula
|
C9H15N5O3
|
|
gptkbp:degradedBy
|
dihydrobiopterin
|
|
gptkbp:foundIn
|
human body
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
tetrahydrobiopterin
|
|
gptkbp:IUPACName
|
2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydropteridin-4(3H)-one
|
|
gptkbp:KEGGID
|
C00526
|
|
gptkbp:MeSH_ID
|
D010718
|
|
gptkbp:molecularWeight
|
241.25 g/mol
|
|
gptkbp:PubChem_CID
|
439327
CHEBI:15372
DB00360
|
|
gptkbp:role
|
cofactor for nitric oxide synthase
cofactor for phenylalanine hydroxylase
cofactor for tryptophan hydroxylase
cofactor for tyrosine hydroxylase
cofactor in amino acid metabolism
|
|
gptkbp:solubility
|
water-soluble
|
|
gptkbp:UNII
|
8PA8022NEJ
|
|
gptkbp:usedAs
|
drug for phenylketonuria
|
|
gptkbp:bfsParent
|
gptkb:phenylalanine_hydroxylase
gptkb:Nitric_oxide_synthase
gptkb:tyrosine_hydroxylase
|
|
gptkbp:bfsLayer
|
7
|