Mixed Lineage Kinase Domain-Like Protein
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:RIPK3
|
| gptkbp:alternativeName |
gptkb:MLKL
|
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases inflammatory diseases |
| gptkbp:discoveredIn |
2012
|
| gptkbp:encodedBy |
MLKL gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
mediates necroptosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mixed Lineage Kinase Domain-Like Protein
|
| gptkbp:involvedIn |
programmed cell death
|
| gptkbp:locatedOnChromosome |
chromosome 16q23.1
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
54 kDa
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
|
| gptkbp:participatedIn |
necroptosis signaling pathway
|
| gptkbp:postTranslationalModification |
phosphorylation
|
| gptkbp:structure |
contains pseudokinase domain
|
| gptkbp:UniProtID |
gptkb:Q8NB16
|
| gptkbp:bfsParent |
gptkb:MLNK
|
| gptkbp:bfsLayer |
7
|