Statements (70)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
nonsteroidal anti-inflammatory drug |
| gptkbp:approvalYear |
2000
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
M01AC06
|
| gptkbp:availableOn |
gptkb:tablet
injection oral suspension |
| gptkbp:brand |
gptkb:Metacam
gptkb:Mobic Vivlodex |
| gptkbp:CASNumber |
71125-38-7
|
| gptkbp:contraindication |
severe renal impairment
active gastrointestinal bleeding severe liver impairment history of asthma with NSAIDs hypersensitivity to meloxicam |
| gptkbp:discoveredBy |
gptkb:Boehringer_Ingelheim
|
| gptkbp:drugClass |
gptkb:NSAID
oxicam |
| gptkbp:eliminationHalfLife |
15-20 hours
|
| gptkbp:excretion |
urine
feces |
| gptkbp:hasMolecularFormula |
C14H13N3O4S2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Meloxicam
|
| gptkbp:interactsWith |
gptkb:SSRIs
gptkb:methotrexate lithium corticosteroids ACE inhibitors diuretics anticoagulants other NSAIDs |
| gptkbp:KEGGID |
D00827
|
| gptkbp:lactationWarning |
caution advised
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
nonsteroidal anti-inflammatory drug
COX-1 inhibitor |
| gptkbp:MedlinePlusID |
a601242
|
| gptkbp:metabolism |
liver
|
| gptkbp:overdoseSymptoms |
nausea
vomiting gastrointestinal bleeding drowsiness |
| gptkbp:pregnancyCategory |
D (US, third trimester)
C (US, first and second trimester) |
| gptkbp:pregnancyWarning |
may cause harm in late pregnancy
|
| gptkbp:proteinBinding |
99%
|
| gptkbp:PubChem_CID |
CHEMBL651
4445392 5281040 |
| gptkbp:routeOfAdministration |
oral
intramuscular intravenous |
| gptkbp:sideEffect |
edema
dizziness headache hypertension rash gastrointestinal upset increased risk of cardiovascular events increased risk of gastrointestinal bleeding |
| gptkbp:UNII |
VG2QF83CGL
|
| gptkbp:usedFor |
gptkb:juvenile_idiopathic_arthritis
osteoarthritis pain relief rheumatoid arthritis inflammation reduction |
| gptkbp:bfsParent |
gptkb:Zentiva
|
| gptkbp:bfsLayer |
7
|