|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
MXA
interferon-induced GTP-binding protein Mx1
|
|
gptkbp:associatedWith
|
gptkb:hepatitis_C
gptkb:SARS-CoV-2_infection
influenza
viral infection resistance
|
|
gptkbp:biologicalProcess
|
GTPase activity
innate immune response
defense response to virus
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
|
|
gptkbp:encodes
|
MX1 protein
|
|
gptkbp:Entrez_Gene_ID
|
4599
ENSG00000157601
|
|
gptkbp:expressedIn
|
gptkb:cancer
liver
spleen
|
|
gptkbp:firstDescribed
|
1986
|
|
gptkbp:fullName
|
MX dynamin like GTPase 1
|
|
gptkbp:function
|
antiviral response
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
7527
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MX1
|
|
gptkbp:inducedBy
|
gptkb:type_I_interferons
|
|
gptkbp:length
|
662 amino acids
|
|
gptkbp:locatedOnChromosome
|
21
21q22.3
|
|
gptkbp:molecularWeight
|
76 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased susceptibility to viral infection
|
|
gptkbp:OMIM
|
147150
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Mx1
Mx2
|
|
gptkbp:proteinFamily
|
gptkb:dynamin_superfamily
|
|
gptkbp:regulates
|
upregulated by interferon-alpha
upregulated by interferon-beta
|
|
gptkbp:structure
|
contains GTP-binding domain
contains dynamin family signature
|
|
gptkbp:UniProtID
|
P20591
|
|
gptkbp:bfsParent
|
gptkb:MXGP
gptkb:Interferon-stimulated_gene
gptkb:MYX
|
|
gptkbp:bfsLayer
|
7
|