Statements (27)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:Canalicular_multispecific_organic_anion_transporter
cMOAT |
gptkbp:associatedWith |
gptkb:Dubin-Johnson_syndrome
|
gptkbp:encodedBy |
gptkb:ABCC2_gene
|
gptkbp:expressedIn |
gptkb:kidney
liver intestine |
gptkbp:fullName |
Multidrug resistance-associated protein 2
|
gptkbp:function |
transports organic anions
involved in drug resistance |
gptkbp:gene |
gptkb:ABCC2
|
https://www.w3.org/2000/01/rdf-schema#label |
MRP2
|
gptkbp:locatedIn |
gptkb:cell_membrane
|
gptkbp:locatedOnChromosome |
gptkb:16q12.1
|
gptkbp:memberOf |
gptkb:ATP-binding_cassette_transporter_family
subfamily C |
gptkbp:OMIM |
601107
|
gptkbp:structure |
contains multiple transmembrane domains
contains two ATP-binding domains |
gptkbp:transportation |
gptkb:methotrexate
anticancer drugs glutathione conjugates bilirubin glucuronides |
gptkbp:UniProtID |
O15438
|
gptkbp:bfsParent |
gptkb:Canalicular_multispecific_organic_anion_transporter
|
gptkbp:bfsLayer |
7
|