Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:TTK
|
| gptkbp:biologicalProcess |
cell division
ATP binding protein serine/threonine kinase activity mitotic cell cycle checkpoint |
| gptkbp:cellularComponent |
gptkb:nucleus
kinetochore |
| gptkbp:discoveredIn |
Saccharomyces cerevisiae (yeast)
|
| gptkbp:encodedBy |
gptkb:TTK_gene
|
| gptkbp:enzymeCommissionNumber |
EC 2.7.11.1
|
| gptkbp:function |
gptkb:protein
mitotic checkpoint kinase |
| gptkbp:gene |
gptkb:TTK
|
| https://www.w3.org/2000/01/rdf-schema#label |
MPS1
|
| gptkbp:involvedIn |
spindle assembly checkpoint
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:mouse
gptkb:yeast |
| gptkbp:phosphorylates |
gptkb:BUB1
gptkb:KNL1 gptkb:MAD1 |
| gptkbp:regulates |
spindle checkpoint signaling
|
| gptkbp:significance |
overexpressed in some cancers
|
| gptkbp:target |
anticancer drugs
|
| gptkbp:UniProtID |
gptkb:P33981
|
| gptkbp:bfsParent |
gptkb:IDUA_gene
|
| gptkbp:bfsLayer |
6
|