Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
gptkb:MLH1_gene
|
| gptkbp:formsComplexWith |
gptkb:PMS2_protein
MLH3 protein PMS1 protein |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA mismatch repair
ATP binding mismatch repair activity |
| https://www.w3.org/2000/01/rdf-schema#label |
MLH1 protein
|
| gptkbp:involvedIn |
cell cycle regulation
genomic stability |
| gptkbp:length |
756 amino acids
|
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
chromosome 3p22.2
|
| gptkbp:mutationAssociatedWith |
gptkb:Lynch_syndrome
gptkb:hereditary_nonpolyposis_colorectal_cancer |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae |
| gptkbp:PDB |
4P7A
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:structure |
heterodimer with PMS2
|
| gptkbp:UniProtID |
P40692
|
| gptkbp:bfsParent |
gptkb:MutL/MLH_family
gptkb:PMS2_protein gptkb:Exonuclease_1_protein |
| gptkbp:bfsLayer |
7
|