MIC-1

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:GDF15
macrophage inhibitory cytokine-1
gptkbp:associatedWith gptkb:cancer
cardiovascular diseases
metabolic disorders
gptkbp:discoveredBy Australian researchers
gptkbp:discoveredIn 1997
gptkbp:expressedIn gptkb:placenta
gptkb:prostate
liver
macrophages
gptkbp:function cellular response to stress
regulation of inflammatory and apoptotic pathways
gptkbp:gene GDF15 gene
https://www.w3.org/2000/01/rdf-schema#label MIC-1
gptkbp:memberOf gptkb:TGF-beta_superfamily
gptkbp:molecularWeight 25 kDa (dimer)
gptkbp:regulates apoptosis
cell growth
immune response
gptkbp:structure dimeric protein
gptkbp:usedAs biomarker for disease
gptkbp:bfsParent gptkb:GDF15
gptkbp:bfsLayer 7