MELK

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alias MPK38
maternal embryonic leucine zipper kinase
gptkbp:associatedWith gptkb:cancer
gptkbp:discoveredBy Nakano et al.
gptkbp:discoveredIn 1997
gptkbp:Entrez_Gene_ID 9833
gptkbp:enzymeCommissionNumber EC 2.7.11.1
gptkbp:expressedIn cancer cells
embryonic tissues
gptkbp:fullName Maternal Embryonic Leucine Zipper Kinase
gptkbp:function serine/threonine protein kinase
gptkbp:gene gptkb:MELK
gptkbp:HGNC_ID HGNC:17445
https://www.w3.org/2000/01/rdf-schema#label MELK
gptkbp:involvedIn apoptosis
cell cycle regulation
stem cell renewal
gptkbp:locatedOnChromosome gptkb:chromosome_9
gptkbp:location gptkb:nucleus
gptkb:cytoplasm
gptkbp:molecularWeight 74 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:phosphorylates gptkb:p53
ASK1
CDC25B
gptkbp:structure contains kinase domain
contains leucine zipper domain
gptkbp:target MELK-8A
OTSSP167
gptkbp:UniProtID Q14680
gptkbp:bfsParent gptkb:Melk_Bahnhof
gptkbp:bfsLayer 7