|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Homeobox_protein_Meis1
myeloid ecotropic viral integration site 1 homolog
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
gptkb:restless_legs_syndrome
|
|
gptkbp:discoveredBy
|
Ruddle FH et al.
|
|
gptkbp:encodes
|
gptkb:Meis_homeobox_1_protein
|
|
gptkbp:Entrez_Gene_ID
|
4211
ENSG00000143995
|
|
gptkbp:expressedIn
|
hematopoietic cells
developing nervous system
|
|
gptkbp:firstDescribed
|
1997
|
|
gptkbp:gene
|
gptkb:MEIS1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0005634
GO:0003700
GO:0006355
|
|
gptkbp:hasMousePhenotype
|
cardiac defects
limb abnormalities
embryonic lethality when knocked out
hematopoietic defects
|
|
gptkbp:hasRefSeqID
|
NM_002398
|
|
gptkbp:hasTranscriptVariants
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:7000
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MEIS1 gene
|
|
gptkbp:interactsWith
|
gptkb:HOXA9_protein
gptkb:PBX1_protein
PREP1 protein
|
|
gptkbp:involvedIn
|
transcriptional regulation
|
|
gptkbp:involves
|
embryonic development
angiogenesis
cardiac development
leukemogenesis
limb development
|
|
gptkbp:locatedOnChromosome
|
gptkb:2p14
chromosome 2
|
|
gptkbp:memberOf
|
gptkb:TALE_homeobox_gene_family
|
|
gptkbp:OMIM
|
601739
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Meis1
|
|
gptkbp:PDB
|
2KHK
2KHL
2KHM
|
|
gptkbp:proteinFamily
|
homeobox domain
TALE domain
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
HOXA9 gene
|
|
gptkbp:UniProtID
|
gptkb:Q99627
|
|
gptkbp:bfsParent
|
gptkb:MEIS1_protein
|
|
gptkbp:bfsLayer
|
7
|