Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
gptkb:gene
|
| gptkbp:contains |
gptkb:MEF2_domain
MADS-box domain |
| gptkbp:discoveredIn |
1992
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
brain cardiac muscle smooth muscle |
| gptkbp:foundIn |
invertebrates
vertebrates |
| gptkbp:fullName |
Myocyte enhancer factor 2 proteins
|
| gptkbp:function |
transcription factor
|
| gptkbp:gene |
gptkb:MEF2C
gptkb:MEF2A gptkb:MEF2D MEF2B |
| https://www.w3.org/2000/01/rdf-schema#label |
MEF2 proteins
|
| gptkbp:interactsWith |
co-activators
HDACs |
| gptkbp:involvedIn |
neuronal differentiation
muscle development cardiac development |
| gptkbp:member |
gptkb:MEF2C
gptkb:MEF2A gptkb:MEF2D MEF2B |
| gptkbp:mutationAssociatedWith |
neurodevelopmental disorders
cardiomyopathy |
| gptkbp:orthologIn |
Drosophila MEF2
|
| gptkbp:phosphorylates |
gptkb:MAPK
gptkb:CaMK |
| gptkbp:regulates |
gptkb:synaptic_plasticity
apoptosis cell differentiation cell survival gene expression immune response cell cycle neurogenesis learning and memory stress response myogenesis axon guidance muscle-specific genes metabolic processes synapse development |
| gptkbp:bfsParent |
gptkb:MyoD1
|
| gptkbp:bfsLayer |
6
|