|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:contains
|
gptkb:MEF2_domain
MADS-box domain
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
cardiac muscle
smooth muscle
|
|
gptkbp:foundIn
|
invertebrates
vertebrates
|
|
gptkbp:fullName
|
Myocyte enhancer factor 2 proteins
|
|
gptkbp:function
|
gptkb:transcription_factor
|
|
gptkbp:gene
|
gptkb:MEF2C
gptkb:MEF2A
gptkb:MEF2D
MEF2B
|
|
gptkbp:interactsWith
|
co-activators
HDACs
|
|
gptkbp:involvedIn
|
neuronal differentiation
muscle development
cardiac development
|
|
gptkbp:member
|
gptkb:MEF2C
gptkb:MEF2A
gptkb:MEF2D
MEF2B
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cardiomyopathy
neurodevelopmental disorders
|
|
gptkbp:orthologIn
|
Drosophila MEF2
|
|
gptkbp:phosphorylates
|
gptkb:MAPK
gptkb:CaMK
|
|
gptkbp:regulates
|
gptkb:immune_response
gptkb:synaptic_plasticity
apoptosis
cell differentiation
cell survival
gene expression
cell cycle
neurogenesis
learning and memory
stress response
myogenesis
axon guidance
muscle-specific genes
metabolic processes
synapse development
|
|
gptkbp:bfsParent
|
gptkb:MyoD1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MEF2 proteins
|