Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Melanoma_Differentiation-Associated_protein_5
Interferon-induced helicase C domain-containing protein 1 |
| gptkbp:associatedWith |
gptkb:dermatomyositis
gptkb:Aicardi-Goutières_syndrome autoimmune diseases |
| gptkbp:discoveredBy |
gptkb:Yoshihiko_Fujita
|
| gptkbp:discoveredIn |
2002
|
| gptkbp:domain |
gptkb:CARD_domain
helicase domain |
| gptkbp:encodedBy |
gptkb:IFIH1_gene
|
| gptkbp:function |
induces type I interferon production
innate immune sensor of viral RNA |
| https://www.w3.org/2000/01/rdf-schema#label |
MDA5 protein
|
| gptkbp:interactsWith |
MAVS protein
|
| gptkbp:locatedIn |
gptkb:cytoplasm
|
| gptkbp:locatedOnChromosome |
chromosome 2q24.2
|
| gptkbp:recognizedBy |
long double-stranded RNA
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
gptkb:Q9BYX4
|
| gptkbp:bfsParent |
gptkb:anti-MDA5
|
| gptkbp:bfsLayer |
6
|