Melanoma Differentiation-Associated protein 5
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:MDA5
|
| gptkbp:associatedWith |
gptkb:Aicardi-Goutières_syndrome
type 1 diabetes autoimmune diseases |
| gptkbp:discoveredBy |
Kang et al.
|
| gptkbp:discoveredIn |
2002
|
| gptkbp:encodedBy |
gptkb:IFIH1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
innate immune response
viral RNA recognition interferon production induction |
| https://www.w3.org/2000/01/rdf-schema#label |
Melanoma Differentiation-Associated protein 5
|
| gptkbp:interactsWith |
viral double-stranded RNA
|
| gptkbp:locatedOnChromosome |
chromosome 2q24.2
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:proteinFamily |
RIG-I-like receptor
|
| gptkbp:structure |
contains helicase domain
contains CARD domain |
| gptkbp:UniProtID |
gptkb:Q9BYX4
|
| gptkbp:bfsParent |
gptkb:MDA5_protein
|
| gptkbp:bfsLayer |
7
|