Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hereditary cancer syndrome
|
| gptkbp:alsoKnownAs |
gptkb:Lynch_syndrome
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:endometrial_cancer colorectal cancer |
| gptkbp:diagnosedBy |
gptkb:Amsterdam_criteria
gptkb:Bethesda_guidelines genetic testing |
| gptkbp:firstDescribed |
gptkb:Henry_T._Lynch
|
| https://www.w3.org/2000/01/rdf-schema#label |
HNPCC
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:managedBy |
genetic counseling
prophylactic surgery regular colonoscopy |
| gptkbp:mutationAssociatedWith |
gptkb:MLH1
gptkb:MSH2 gptkb:MSH6 gptkb:PMS2 gptkb:EPCAM |
| gptkbp:prevalence |
2-4% of all colorectal cancers
|
| gptkbp:riskFactor |
gptkb:small_bowel_cancer
brain cancer gastric cancer urinary tract cancer hepatobiliary cancer |
| gptkbp:bfsParent |
gptkb:Lynch_syndrome
|
| gptkbp:bfsLayer |
5
|