Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cytokine |
| gptkbp:alternativeName |
gptkb:TNF-beta
LT-alpha lymphotoxin |
| gptkbp:associatedWith |
autoimmune diseases
inflammatory diseases |
| gptkbp:discoveredBy |
1968
|
| gptkbp:encodedBy |
gptkb:LTA_gene
|
| gptkbp:Entrez_Gene_ID |
4049
|
| gptkbp:expressedIn |
activated lymphocytes
|
| gptkbp:formsComplexWith |
Lymphotoxin beta
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
mediates inflammation
induces cell death |
| gptkbp:HGNC_ID |
6720
|
| https://www.w3.org/2000/01/rdf-schema#label |
Lymphotoxin alpha
|
| gptkbp:involvedIn |
immune response
lymphoid organ development |
| gptkbp:length |
171 amino acids
|
| gptkbp:locatedOnChromosome |
chromosome 6p21.3
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_superfamily
|
| gptkbp:OMIM |
153440
|
| gptkbp:PDB |
gptkb:1TNR
|
| gptkbp:recipient |
TNF receptor 1
TNF receptor 2 |
| gptkbp:regulates |
apoptosis
cell proliferation |
| gptkbp:structure |
homotrimer
heterotrimer with LT-beta |
| gptkbp:UniProtID |
P01374
|
| gptkbp:bfsParent |
gptkb:LTA
|
| gptkbp:bfsLayer |
5
|