|
gptkbp:instanceOf
|
gptkb:cancer
|
|
gptkbp:alternativeName
|
LCLC
undifferentiated carcinoma of the lung
|
|
gptkbp:diagnosedBy
|
gptkb:CT_scan
PET scan
biopsy
histopathology
|
|
gptkbp:hasCommonSymptoms
|
weight loss
cough
shortness of breath
chest pain
|
|
gptkbp:hasFirstDescribed
|
1930s
|
|
gptkbp:hasGeneticAlteration
|
gptkb:TP53_mutation
gptkb:KRAS_mutation
EGFR mutation (rare)
|
|
gptkbp:hasLocation
|
gptkb:cancer
|
|
gptkbp:hasMedianSurvival
|
8-12 months (advanced stage)
|
|
gptkbp:hasMetastasisSite
|
gptkb:bone
brain
liver
adrenal glands
|
|
gptkbp:hasType
|
large undifferentiated cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Large cell lung cancer
|
|
gptkbp:ICD-10_code
|
C34
|
|
gptkbp:prevalence
|
less common than adenocarcinoma and squamous cell carcinoma
|
|
gptkbp:prognosis
|
stage at diagnosis
presence of metastasis
performance status
generally poor
|
|
gptkbp:riskFactor
|
gptkb:air_pollution
smoking
asbestos exposure
exposure to radon
|
|
gptkbp:stageName
|
gptkb:TNM_staging
|
|
gptkbp:subspecies
|
gptkb:non-small_cell_lung_cancer
gptkb:cancer
gptkb:basaloid_carcinoma
gptkb:large_cell_neuroendocrine_carcinoma
lymphoepithelioma-like carcinoma
rhabdoid variant
|
|
gptkbp:treatment
|
surgery
radiation therapy
chemotherapy
immunotherapy
|
|
gptkbp:bfsParent
|
gptkb:Large_Cell_Carcinoma
|
|
gptkbp:bfsLayer
|
7
|