Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
leukemia |
| gptkbp:affects |
large granular lymphocytes
|
| gptkbp:associatedWith |
autoimmune disorders
rheumatoid arthritis |
| gptkbp:diagnosedBy |
immunophenotyping
blood smear flow cytometry T-cell receptor gene rearrangement |
| gptkbp:firstDescribed |
1985
|
| gptkbp:gender |
slightly more common in males
|
| gptkbp:hasEpidemiology |
rare
|
| https://www.w3.org/2000/01/rdf-schema#label |
LGL leukemia
|
| gptkbp:medianAge |
60 years
|
| gptkbp:mutationAssociatedWith |
gptkb:STAT3_mutation
gptkb:STAT5b_mutation |
| gptkbp:prognosis |
generally indolent
|
| gptkbp:subspecies |
leukemia
T-cell LGL leukemia chronic lymphoproliferative disorder of NK cells |
| gptkbp:symptom |
gptkb:anemia
fatigue neutropenia recurrent infections |
| gptkbp:treatment |
gptkb:cyclophosphamide
gptkb:cyclosporine gptkb:methotrexate immunosuppressive therapy |
| gptkbp:bfsParent |
gptkb:LGL_Lymphocytosis
gptkb:Large_Granular_Lymphocyte_Leukemia |
| gptkbp:bfsLayer |
8
|