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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
Large tumor suppressor kinase 2
|
|
gptkbp:associatedWith
|
tumor suppression
|
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gptkbp:encodedBy
|
LATS2 gene
|
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gptkbp:function
|
protein serine/threonine kinase activity
serine/threonine-protein kinase
|
|
gptkbp:GOProcess
|
negative regulation of cell proliferation
positive regulation of apoptotic process
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LATS2 protein
|
|
gptkbp:interactsWith
|
gptkb:SAV1_protein
MOB1 protein
WW45 protein
|
|
gptkbp:involvedIn
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gptkb:Hippo_signaling_pathway
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:locatedOnChromosome
|
13q12.11
|
|
gptkbp:molecularWeight
|
120 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
6O5J
|
|
gptkbp:phosphorylates
|
gptkb:TAZ_protein
gptkb:YAP1_protein
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
cell cycle
|
|
gptkbp:UniProtID
|
Q9NRM7
|
|
gptkbp:bfsParent
|
gptkb:WW_domain
|
|
gptkbp:bfsLayer
|
7
|