Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Large tumor suppressor kinase 1
|
| gptkbp:associatedWith |
tumor suppression
|
| gptkbp:encodedBy |
LATS1 gene
|
| gptkbp:Entrez_Gene_ID |
9113
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
serine/threonine-protein kinase
|
| https://www.w3.org/2000/01/rdf-schema#label |
LATS1 protein
|
| gptkbp:interactsWith |
CDC2 protein
MOB1 protein WW45 protein |
| gptkbp:involvedIn |
gptkb:Hippo_signaling_pathway
|
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
10q21.3
|
| gptkbp:molecularWeight |
127 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster |
| gptkbp:PDB |
6O5J
|
| gptkbp:phosphorylates |
gptkb:TAZ_protein
gptkb:YAP1_protein |
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:regulates |
apoptosis
cell proliferation |
| gptkbp:UniProtID |
O95835
|
| gptkbp:bfsParent |
gptkb:WW_domain
|
| gptkbp:bfsLayer |
7
|