|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:malate_dehydrogenase
|
|
gptkbp:biologicalProcess
|
oxidoreductase activity
|
|
gptkbp:CASNumber
|
9001-62-1
|
|
gptkbp:catalyzes
|
oxidation of malate to oxaloacetate
|
|
gptkbp:cofactor
|
NAD+
|
|
gptkbp:EC_number
|
1.1.1.37
|
|
gptkbp:foundIn
|
gptkb:cytoplasm
mitochondria
|
|
gptkbp:gene
|
gptkb:MDH1
gptkb:MDH2
|
|
gptkbp:GO_term
|
GO:0016615
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
L-malate dehydrogenase
|
|
gptkbp:inhibitedBy
|
gptkb:oxaloacetate
malonate
|
|
gptkbp:involves
|
citric acid cycle
|
|
gptkbp:presentIn
|
gptkb:Bacteria
animals
fungi
plants
archaea
|
|
gptkbp:product
|
gptkb:H+
gptkb:NADH
gptkb:oxaloacetate
|
|
gptkbp:reaction_equation
|
(S)-malate + NAD+ ⇌ oxaloacetate + NADH + H+
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:L-malate
|
|
gptkbp:systematicName
|
gptkb:(S)-malate:NAD+_oxidoreductase
|
|
gptkbp:UniProt_ID_(human,_cytosolic)
|
P40925
|
|
gptkbp:UniProt_ID_(human,_mitochondrial)
|
P40926
|
|
gptkbp:used_in
|
gptkb:malate-aspartate_shuttle
|
|
gptkbp:bfsParent
|
gptkb:Malate_dehydrogenase
|
|
gptkbp:bfsLayer
|
7
|