Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:MDH
gptkb:malic_dehydrogenase |
| gptkbp:biologicalProcess |
oxidoreductase activity
|
| gptkbp:CASNumber |
9001-63-2
|
| gptkbp:catalyzes |
oxidation of malate to oxaloacetate
|
| gptkbp:cofactor |
gptkb:NADH
NAD+ |
| gptkbp:EC_number |
1.1.1.37
|
| gptkbp:foundIn |
gptkb:cytoplasm
mitochondria |
| gptkbp:gene |
gptkb:MDH1
gptkb:MDH2 |
| https://www.w3.org/2000/01/rdf-schema#label |
malate dehydrogenase
|
| gptkbp:inhibitedBy |
high NADH/NAD+ ratio
oxaloacetate (product inhibition) |
| gptkbp:involves |
gptkb:malate-aspartate_shuttle
citric acid cycle |
| gptkbp:presentIn |
gptkb:Bacteria
animals plants |
| gptkbp:product |
gptkb:H+
gptkb:NADH gptkb:oxaloacetate |
| gptkbp:requires |
energy metabolism
gluconeogenesis |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
malate
|
| gptkbp:systematicName |
gptkb:(S)-malate:NAD+_oxidoreductase
|
| gptkbp:UniProt_ID_(human_cytosolic) |
P40925
|
| gptkbp:UniProt_ID_(human_mitochondrial) |
P40926
|
| gptkbp:bfsParent |
gptkb:Krebs_cycle
|
| gptkbp:bfsLayer |
5
|