Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
|
gptkbp:alsoKnownAs |
gptkb:Kumada–Corriu_coupling
|
gptkbp:application |
pharmaceutical chemistry
organic synthesis |
gptkbp:category |
organometallic chemistry
transition metal catalysis |
gptkbp:field |
chemistry
|
gptkbp:firstReported |
1972
|
https://www.w3.org/2000/01/rdf-schema#label |
Kumada coupling
|
gptkbp:involves |
gptkb:Grignard_reagent
aryl halide vinyl halide palladium catalyst nickel catalyst |
gptkbp:mechanismOfAction |
oxidative addition
reductive elimination transmetalation |
gptkbp:namedAfter |
gptkb:Jean-Pierre_Corriu
gptkb:Makoto_Kumada |
gptkbp:product |
biaryl compound
alkene |
gptkbp:relatedTo |
gptkb:Negishi_coupling
gptkb:Heck_reaction gptkb:Suzuki_coupling gptkb:Stille_coupling |
gptkbp:requires |
inert atmosphere
anhydrous conditions |
gptkbp:solvent |
gptkb:THF
Ether |
gptkbp:type |
cross-coupling reaction
|
gptkbp:bfsParent |
gptkb:Negishi_coupling
|
gptkbp:bfsLayer |
6
|