Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
pharmaceutical chemistry
organic synthesis |
| gptkbp:catalyzes |
palladium complex
|
| gptkbp:field |
organometallic chemistry
synthetic organic chemistry |
| gptkbp:firstReported |
1977
|
| https://www.w3.org/2000/01/rdf-schema#label |
Stille coupling
|
| gptkbp:involves |
organic halide
organotin compound |
| gptkbp:limitation |
removal of tin residues
toxicity of organotin compounds |
| gptkbp:mechanismOfAction |
oxidative addition
reductive elimination transmetalation |
| gptkbp:namedAfter |
gptkb:John_Kenneth_Stille
|
| gptkbp:product |
biaryl compound
alkene alkyne |
| gptkbp:relatedTo |
gptkb:Negishi_coupling
gptkb:Heck_reaction gptkb:Suzuki_coupling |
| gptkbp:sideEffect |
organotin waste
|
| gptkbp:solvent |
gptkb:THF
gptkb:DMF toluene |
| gptkbp:temperature |
room temperature
reflux |
| gptkbp:type |
cross-coupling reaction
|
| gptkbp:bfsParent |
gptkb:Negishi_coupling
|
| gptkbp:bfsLayer |
6
|