Suzuki coupling

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf chemical reaction
gptkbp:application synthesis of agrochemicals
synthesis of natural products
synthesis of polymers
gptkbp:awards gptkb:Akira_Suzuki
gptkbp:base sodium hydroxide
potassium carbonate
gptkbp:chemicalFormula oxidative addition
reductive elimination
transmetalation
gptkbp:climate room temperature to elevated temperatures
gptkbp:collaborations gptkb:Richard_F._Heck
gptkb:Ei-ichi_Negishi
gptkbp:condition base required
gptkbp:dissolved ethanol
water
toluene
gptkbp:firstPublished 1979
gptkbp:hasDepartment requires anhydrous conditions
sensitive to functional groups
https://www.w3.org/2000/01/rdf-schema#label Suzuki coupling
gptkbp:industry widely used in agrochemicals
widely used in materials science
widely used in pharmaceuticals
gptkbp:ingredients aryl halides
organoboranes
gptkbp:involves cross-coupling reaction
gptkbp:is_used_in material science
pharmaceutical development
gptkbp:judgingCriteria high regioselectivity
high stereoselectivity
gptkbp:notableWork gptkb:Nobel_Prize_in_Chemistry_2010
gptkbp:produces gptkb:Akira_Suzuki
generally high yields
gptkbp:products biaryl compounds
gptkbp:related_to gptkb:Negishi_coupling
Heck reaction
Stille_coupling
gptkbp:research_focus developing greener methods
expanding substrate scope
improving catalyst efficiency
gptkbp:responseTime typically short reaction times
gptkbp:safety handling of organoboranes
handling of palladium compounds
gptkbp:suitableFor organic synthesis
gptkbp:uses palladium catalyst
gptkbp:was_a_catalyst_for Palladium nanoparticles
Palladium(0) complexes
Palladium(II) complexes