Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:domain |
zinc finger domain
|
| gptkbp:encodedBy |
KLF2 gene
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:thymus heart endothelial cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of gene expression
vascular development endothelial cell function |
| https://www.w3.org/2000/01/rdf-schema#label |
Kruppel-like factor 2
|
| gptkbp:regulates |
apoptosis
cell proliferation lipid metabolism cellular senescence angiogenesis glucose metabolism inflammation oxidative stress response cell cycle arrest hematopoiesis cardiac development lung development VCAM-1 expression endothelial barrier function immune cell migration endothelial activation vascular permeability vascular smooth muscle cell proliferation vascular remodeling vascular tone ICAM-1 expression T cell trafficking anti-inflammatory genes eNOS expression monocyte adhesion thrombomodulin expression embryonic vascular development lymphocyte egress vascular homeostasis vascular inflammation arterial specification blood vessel stability endothelial quiescence shear stress response vascular smooth muscle cell migration |
| gptkbp:bfsParent |
gptkb:KLF2
|
| gptkbp:bfsLayer |
8
|