Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:alternativeName |
gptkb:EKLF
|
| gptkbp:discoveredBy |
1993
|
| gptkbp:domain |
zinc finger domain
|
| gptkbp:expressedIn |
erythroid cells
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of erythroid cell development
regulation of beta-globin gene expression |
| gptkbp:gene |
gptkb:KLF1
gptkb:KLF1_gene |
| gptkbp:HGNC_ID |
HGNC:6346
|
| https://www.w3.org/2000/01/rdf-schema#label |
Kruppel-like factor 1
|
| gptkbp:locatedOnChromosome |
chromosome 19p13.13
|
| gptkbp:mutationAssociatedWith |
gptkb:congenital_dyserythropoietic_anemia_type_IV
gptkb:hereditary_persistence_of_fetal_hemoglobin |
| gptkbp:OMIM |
600599
|
| gptkbp:proteinFamily |
gptkb:Kruppel-like_factors
|
| gptkbp:regulates |
gptkb:BCL11A
gptkb:beta-globin_gene gptkb:CD44_gene gptkb:HBB_gene erythropoiesis HBG1 gene HBG2 gene ANK1 gene EPB42 gene SLC4A1 gene KLF11 gene KLF8 gene AHSP gene ALAS2 gene E2F2 gene GATA1 gene GATA2 gene GYPB gene GYPE gene ICAM4 gene KLF10 gene KLF12 gene KLF13 gene KLF14 gene KLF15 gene KLF16 gene KLF17 gene KLF18 gene KLF19 gene KLF2 gene KLF20 gene KLF21 gene KLF22 gene KLF23 gene KLF3 gene KLF6 gene KLF9 gene alpha-globin gene |
| gptkbp:UniProtID |
Q13351
|
| gptkbp:bfsParent |
gptkb:KLF1
|
| gptkbp:bfsLayer |
7
|