hereditary persistence of fetal hemoglobin
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
hematological disorder |
| gptkbp:abbreviation |
HPFH
|
| gptkbp:affects |
hemoglobin production
|
| gptkbp:canBe |
benign
asymptomatic |
| gptkbp:causedBy |
genetic mutations
|
| gptkbp:characterizedBy |
continued production of fetal hemoglobin into adulthood
|
| gptkbp:coexistedWith |
gptkb:beta-thalassemia
sickle cell disease |
| gptkbp:diagnosedBy |
genetic testing
hemoglobin electrophoresis |
| gptkbp:firstDescribed |
1960s
|
| https://www.w3.org/2000/01/rdf-schema#label |
hereditary persistence of fetal hemoglobin
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:involves |
gptkb:gamma-globin_gene
beta-globin gene cluster |
| gptkbp:prevalence |
rare
|
| gptkbp:relatedTo |
gptkb:anemia
hemoglobinopathies |
| gptkbp:treatment |
usually not required
|
| gptkbp:bfsParent |
gptkb:EKLF
gptkb:KLF1 gptkb:HBG1 gptkb:HBG2 |
| gptkbp:bfsLayer |
7
|