Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
Inward rectifier potassium channel 2.x
|
| gptkbp:encodedBy |
KCNJ gene family
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
brain heart |
| gptkbp:foundIn |
mammals
|
| gptkbp:function |
potassium ion transport
maintenance of resting membrane potential |
| gptkbp:hasMember |
gptkb:Kir2.1
Kir2.2 Kir2.3 Kir2.4 |
| https://www.w3.org/2000/01/rdf-schema#label |
Kir2.x
|
| gptkbp:memberOf |
inward rectifier potassium channels
|
| gptkbp:permeableTo |
potassium ions
|
| gptkbp:regulates |
regulated by Mg2+
regulated by intracellular polyamines |
| gptkbp:significance |
mutations can cause Andersen-Tawil syndrome
mutations can cause cardiac arrhythmias |
| gptkbp:structure |
tetrameric
|
| gptkbp:subfamily |
gptkb:Kir_channels
|
| gptkbp:bfsParent |
gptkb:KIR2.1
gptkb:inwardly_rectifying_potassium_channels |
| gptkbp:bfsLayer |
7
|