|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:IRK1
gptkb:KCNJ2
inward rectifier potassium channel 2
|
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gptkbp:associatedWith
|
gptkb:Andersen-Tawil_syndrome
gptkb:arrhythmia
|
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gptkbp:encodedBy
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gptkb:KCNJ2
|
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gptkbp:foundIn
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gptkb:human
gptkb:skeletal_muscle
brain
cardiac muscle
|
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gptkbp:function
|
potassium ion transport
maintenance of resting membrane potential
|
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gptkbp:gene
|
gptkb:KCNJ2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Kir2.1
|
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gptkbp:locatedOnChromosome
|
17q24.3
|
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gptkbp:memberOf
|
inward-rectifier potassium channel family
|
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gptkbp:molecularWeight
|
~48 kDa
|
|
gptkbp:mutationAssociatedWith
|
causes periodic paralysis
causes ventricular arrhythmia
|
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gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:PDB
|
1U4F
|
|
gptkbp:regulates
|
inhibited by intracellular Mg2+
inhibited by polyamines
regulated by PIP2
|
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gptkbp:structure
|
tetramer
|
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gptkbp:subunit
|
potassium channel
|
|
gptkbp:UniProtID
|
P63252
|
|
gptkbp:bfsParent
|
gptkb:IRK1
gptkb:KCNJ2
gptkb:inward_rectifier_potassium_channel_1
gptkb:potassium_channel,_inwardly_rectifying_subfamily_J,_member_2
gptkb:potassium_inwardly_rectifying_channel_subfamily_J_member_2
|
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gptkbp:bfsLayer
|
7
|