Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:SETDB1
|
| gptkbp:amendedBy |
gptkb:histone_H3
lysine 9 methylation |
| gptkbp:associatedWith |
gptkb:cancer
neurodevelopmental disorders |
| gptkbp:biologicalProcess |
histone H3-K9 methylation
|
| gptkbp:encodes |
Histone-lysine N-methyltransferase SETDB1
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000143374
9869 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
epigenetic regulation
histone methyltransferase activity |
| gptkbp:HGNC_ID |
HGNC:29079
|
| https://www.w3.org/2000/01/rdf-schema#label |
KMT1E
|
| gptkbp:interactsWith |
gptkb:TRIM28
KRAB-ZFPs |
| gptkbp:involvedIn |
gene silencing
heterochromatin formation |
| gptkbp:locatedOnChromosome |
1q21.3
|
| gptkbp:OMIM |
604396
|
| gptkbp:orthologInMouse |
Setdb1
|
| gptkbp:proteinFamily |
gptkb:post-SET_domain
SET domain pre-SET domain MBD domain |
| gptkbp:regulates |
transcriptional repression
|
| gptkbp:UniProtID |
gptkb:Q15047
|
| gptkbp:bfsParent |
gptkb:SETDB1
|
| gptkbp:bfsLayer |
7
|