Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:associatedWith |
gptkb:atopic_dermatitis
asthma allergic rhinitis |
| gptkbp:discoveredIn |
1982
|
| gptkbp:enemyOf |
gptkb:Dupilumab
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000113520
3565 |
| gptkbp:function |
induces class switching to IgE
promotes Th2 cell differentiation stimulates B-cell proliferation |
| gptkbp:gene |
gptkb:IL4
|
| gptkbp:HGNC_ID |
6014
|
| https://www.w3.org/2000/01/rdf-schema#label |
Interleukin 4
|
| gptkbp:inhibitedBy |
Th1 cell differentiation
|
| gptkbp:involvedIn |
allergic response
immune regulation |
| gptkbp:locatedOnChromosome |
5q31.1
|
| gptkbp:molecularWeight |
15 kDa
|
| gptkbp:OMIM |
147780
|
| gptkbp:producedBy |
gptkb:basophils
gptkb:mast_cells activated T cells |
| gptkbp:promotion |
IgE production
B cell growth |
| gptkbp:recipient |
gptkb:IL-4_receptor
|
| gptkbp:regulates |
macrophage activation
MHC class II expression |
| gptkbp:structure |
four-helix bundle
|
| gptkbp:symbol |
gptkb:IL-4
|
| gptkbp:UniProtID |
P05112
|
| gptkbp:bfsParent |
gptkb:IL4
|
| gptkbp:bfsLayer |
6
|