Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:abbreviation |
gptkb:IL-1
|
| gptkbp:category |
pro-inflammatory cytokine
|
| gptkbp:composedOf |
gptkb:Interleukin-1_beta
Interleukin-1 alpha |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
IL1A gene
IL1B gene |
| gptkbp:function |
mediates inflammatory response
induces fever stimulates immune cells |
| gptkbp:GO_term |
gptkb:GO:0005125
|
| https://www.w3.org/2000/01/rdf-schema#label |
Interleukin-1
|
| gptkbp:MeSH_ID |
gptkb:D015850
|
| gptkbp:producedBy |
dendritic cells
macrophages monocytes |
| gptkbp:recipient |
Interleukin-1 receptor
|
| gptkbp:relatedTo |
Interleukin-1 receptor antagonist
Interleukin-18 |
| gptkbp:role |
gptkb:cancer
infectious diseases sepsis autoimmune diseases rheumatoid arthritis |
| gptkbp:target |
gptkb:canakinumab
gptkb:anakinra rilonacept |
| gptkbp:UNII |
Q9Y6Y9
|
| gptkbp:bfsParent |
gptkb:IL-1
|
| gptkbp:bfsLayer |
7
|