Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
interleukin-1 receptor antagonist |
gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2001 |
gptkbp:ATCCode |
L04AC03
|
gptkbp:brand |
gptkb:Kineret
|
gptkbp:CASNumber |
143090-92-0
|
gptkbp:contraindication |
active infections
hypersensitivity to anakinra |
gptkbp:developedBy |
gptkb:Amgen
|
gptkbp:hasMolecularFormula |
C759H1186N208O227S10
|
https://www.w3.org/2000/01/rdf-schema#label |
anakinra
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
blocks interleukin-1
|
gptkbp:pregnancyCategory |
C (US)
|
gptkbp:product |
recombinant, non-glycosylated form of human IL-1Ra
|
gptkbp:routeOfAdministration |
subcutaneous injection
|
gptkbp:sideEffect |
injection site reaction
neutropenia increased risk of infection |
gptkbp:UNII |
28Y2K4NN2O
|
gptkbp:usedFor |
gptkb:Still's_disease
gptkb:cryopyrin-associated_periodic_syndromes rheumatoid arthritis neonatal-onset multisystem inflammatory disease |
gptkbp:bfsParent |
gptkb:interleukin-1
|
gptkbp:bfsLayer |
6
|