Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:interleukin-1_receptor_antagonist
gptkb:drug |
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2001 |
| gptkbp:ATCCode |
L04AC03
|
| gptkbp:brand |
gptkb:Kineret
|
| gptkbp:CASNumber |
143090-92-0
|
| gptkbp:contraindication |
active infections
hypersensitivity to anakinra |
| gptkbp:developedBy |
gptkb:Amgen
|
| gptkbp:hasMolecularFormula |
C759H1186N208O227S10
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
blocks interleukin-1
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:product |
recombinant, non-glycosylated form of human IL-1Ra
|
| gptkbp:routeOfAdministration |
subcutaneous injection
|
| gptkbp:sideEffect |
injection site reaction
neutropenia increased risk of infection |
| gptkbp:UNII |
28Y2K4NN2O
|
| gptkbp:usedFor |
gptkb:Still's_disease
gptkb:cryopyrin-associated_periodic_syndromes rheumatoid arthritis neonatal-onset multisystem inflammatory disease |
| gptkbp:bfsParent |
gptkb:IL-1
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
anakinra
|