Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:the_4th_Air_Army
gptkb:The_Stalingrad_Airlift gptkb:Red_Air_Force |
| gptkbp:associated_with |
autoimmune disorders
chronic infections |
| gptkbp:discovered_by |
gptkb:Robert_G._Miller
|
| gptkbp:enhances |
cytokine production
cytotoxic T cell activity monocyte activation |
| gptkbp:established |
apoptosis of T cells
|
| gptkbp:first_described_by |
gptkb:1983
|
| gptkbp:function |
stimulates T cell proliferation
|
| https://www.w3.org/2000/01/rdf-schema#label |
Il-2
|
| gptkbp:increased |
NK cell activity
|
| gptkbp:influences |
cell differentiation
metabolic processes inflammation cell survival immune evasion mechanisms tumor microenvironment immune tolerance therapeutic outcomes tissue repair thymocyte development antibody production immune response regulation immune cell function cytokine signaling immune cell proliferation immune checkpoint regulation immune system homeostasis immune cell migration immune memory B cell differentiation cell activation |
| gptkbp:ingredients |
alpha, beta, and gamma chains
|
| gptkbp:is_involved_in |
gptkb:healthcare_organization
immune response allergic reactions viral infections bacterial infections humoral immunity tumor immunity cellular immunity parasitic infections |
| gptkbp:is_vulnerable_to |
gptkb:IL-2_receptor
|
| gptkbp:location |
chromosome 4
|
| gptkbp:produced_by |
gptkb:T_cells
memory T cells response to antigen |
| gptkbp:promoter |
I L2
|
| gptkbp:research_areas |
gptkb:healthcare_organization
autoimmune diseases |
| gptkbp:role |
Treg cell development
|
| gptkbp:targets |
B cells
NK cells |
| gptkbp:used_in |
gptkb:vaccine
|