Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
zinc
|
| gptkbp:confers_resistance_to |
carbapenem antibiotics
|
| gptkbp:discoveredBy |
gptkb:Japan
|
| gptkbp:EC_number |
3.5.2.6
|
| gptkbp:firstReported |
1991
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa gptkb:Acinetobacter_baumannii |
| gptkbp:fullName |
gptkb:Imipenemase-1
|
| gptkbp:function |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:gene |
gptkb:blaIMP-1
|
| https://www.w3.org/2000/01/rdf-schema#label |
IMP-1
|
| gptkbp:inhibitedBy |
gptkb:EDTA
|
| gptkbp:mechanismOfAction |
metallo-beta-lactamase
|
| gptkbp:not_inhibited_by |
gptkb:clavulanic_acid
gptkb:sulbactam tazobactam |
| gptkbp:publicHealthConcern |
multidrug resistance
|
| gptkbp:relatedTo |
gptkb:NDM-1
gptkb:VIM-1 |
| gptkbp:significance |
antibiotic resistance
|
| gptkbp:spreadTo |
plasmids
|
| gptkbp:bfsParent |
gptkb:Interplanetary_Monitoring_Platform_(IMP)
|
| gptkbp:bfsLayer |
7
|