IL 25

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf cytokine
gptkbp:alsoKnownAs IL-17E
Interleukin-25
gptkbp:associatedWith gptkb:atopic_dermatitis
asthma
inflammatory bowel disease
gptkbp:discoveredIn 2001
gptkbp:encodedBy IL25 gene
gptkbp:function involved in allergic inflammation
induces production of IL-4, IL-5, and IL-13
involved in defense against helminth infections
promotes Th2-type immune responses
https://www.w3.org/2000/01/rdf-schema#label IL 25
gptkbp:inducedBy eosinophilia
mucus production
gptkbp:length 177 amino acids
gptkbp:locatedOnChromosome 14q11.2
gptkbp:memberOf gptkb:interleukin-17_family
gptkbp:molecularWeight 19.8 kDa
gptkbp:producedBy gptkb:mast_cells
gptkb:T_helper_2_cells
gptkb:eosinophils
epithelial cells
gptkbp:promotion type 2 innate lymphoid cells (ILC2s)
gptkbp:recipient IL-17RB
gptkbp:regulates immune response
gptkbp:species gptkb:Homo_sapiens
gptkbp:structure homodimer
gptkbp:UniProtID Q9H293
gptkbp:bfsParent gptkb:IL_31
gptkb:IL_59
gptkbp:bfsLayer 8