IL4 (human)

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf cytokine
gptkbp:discoveredBy 1982
gptkbp:encodedBy gptkb:IL4_gene
gptkbp:fullName Interleukin-4
gptkbp:function B cell differentiation
regulation of immune response
T helper 2 (Th2) cell differentiation
class switching to IgE and IgG1
gptkbp:gene gptkb:IL4
gptkbp:GO gptkb:GO:0005125
https://www.w3.org/2000/01/rdf-schema#label IL4 (human)
gptkbp:length 153 amino acids
gptkbp:locatedOnChromosome 5q31.1
gptkbp:molecularWeight 15 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Il4 (mouse)
gptkbp:PDB 2B8U
gptkbp:producedBy gptkb:basophils
gptkb:mast_cells
activated T cells
gptkbp:recipient gptkb:IL-4_receptor
gptkbp:regulates inflammation
antibody production
macrophage polarization
gptkbp:significance asthma
allergic diseases
immunotherapy target
gptkbp:structure monomeric glycoprotein
gptkbp:UniProtID P05112
gptkbp:bfsParent gptkb:Il4
gptkbp:bfsLayer 7