Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
cytokine
|
gptkbp:discoveredBy |
1982
|
gptkbp:encodedBy |
gptkb:IL4_gene
|
gptkbp:fullName |
Interleukin-4
|
gptkbp:function |
B cell differentiation
regulation of immune response T helper 2 (Th2) cell differentiation class switching to IgE and IgG1 |
gptkbp:gene |
gptkb:IL4
|
gptkbp:GO |
gptkb:GO:0005125
|
https://www.w3.org/2000/01/rdf-schema#label |
IL4 (human)
|
gptkbp:length |
153 amino acids
|
gptkbp:locatedOnChromosome |
5q31.1
|
gptkbp:molecularWeight |
15 kDa
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:orthologInMouse |
Il4 (mouse)
|
gptkbp:PDB |
2B8U
|
gptkbp:producedBy |
gptkb:basophils
gptkb:mast_cells activated T cells |
gptkbp:recipient |
gptkb:IL-4_receptor
|
gptkbp:regulates |
inflammation
antibody production macrophage polarization |
gptkbp:significance |
asthma
allergic diseases immunotherapy target |
gptkbp:structure |
monomeric glycoprotein
|
gptkbp:UniProtID |
P05112
|
gptkbp:bfsParent |
gptkb:Il4
|
gptkbp:bfsLayer |
7
|