Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:actsOn |
gptkb:NK_cells
gptkb:B_cells gptkb:T_cells |
| gptkbp:clinicalResearch |
gptkb:cancer
infectious diseases autoimmune diseases |
| gptkbp:composedOf |
EBI3
IL-27p28 |
| gptkbp:discoveredIn |
2002
|
| gptkbp:fullName |
Interleukin-27
|
| gptkbp:function |
regulation of immune response
anti-inflammatory effects inhibition of Th17 cell development promotion of Th1 cell differentiation |
| gptkbp:gene |
IL27
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL-27
|
| gptkbp:inhibitedBy |
inflammatory cytokine production
|
| gptkbp:locatedOnChromosome |
16p11
|
| gptkbp:producedBy |
antigen-presenting cells
|
| gptkbp:promotion |
gptkb:STAT3_pathway
STAT1 pathway |
| gptkbp:recipient |
IL-27 receptor
|
| gptkbp:relatedTo |
IL-12 family
|
| gptkbp:bfsParent |
gptkb:SRF388
gptkb:IL-6_family_cytokine_signaling |
| gptkbp:bfsLayer |
8
|