IFIH1 protein

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:MDA5
Melanoma differentiation-associated protein 5
gptkbp:associatedWith gptkb:Aicardi-Goutières_syndrome
type 1 diabetes
autoimmune diseases
gptkbp:biologicalProcess ATP binding
antiviral defense
RNA helicase activity
interferon production
gptkbp:domain gptkb:CARD_domain
DEAD box helicase domain
gptkbp:encodedBy gptkb:IFIH1_gene
gptkbp:function innate immune response
viral RNA recognition
https://www.w3.org/2000/01/rdf-schema#label IFIH1 protein
gptkbp:interactsWith viral double-stranded RNA
MAVS protein
gptkbp:length 1025 amino acids
gptkbp:locatedOnChromosome gptkb:2q24.2
gptkbp:location gptkb:cytoplasm
gptkbp:molecularWeight 116 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:UniProtID gptkb:Q9BYX4
gptkbp:bfsParent gptkb:MDA5
gptkbp:bfsLayer 8