Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:associatedWith |
mutations linked to retinitis pigmentosa
|
| gptkbp:cofactor |
NAD+
|
| gptkbp:EC_number |
1.1.1.41
|
| gptkbp:fullName |
isocitrate dehydrogenase 3
|
| gptkbp:function |
catalyzes the oxidative decarboxylation of isocitrate to alpha-ketoglutarate
|
| gptkbp:gene |
gptkb:IDH3A
gptkb:IDH3B gptkb:IDH3G |
| https://www.w3.org/2000/01/rdf-schema#label |
IDH3
|
| gptkbp:location |
mitochondria
|
| gptkbp:molecularWeight |
~150 kDa
|
| gptkbp:pathway |
citric acid cycle
|
| gptkbp:regulates |
allosterically regulated by ADP and ATP
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:subunit |
gptkb:IDH3A
gptkb:IDH3B gptkb:IDH3G heterotetramer |
| gptkbp:type |
isocitrate + NAD+ → alpha-ketoglutarate + CO2 + NADH
|
| gptkbp:bfsParent |
gptkb:isocitrate_dehydrogenase
|
| gptkbp:bfsLayer |
6
|