Hypothalamic–pituitary–adrenal axis
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:abbreviation |
gptkb:HPA_axis
|
| gptkbp:component |
gptkb:pituitary_gland
gptkb:adrenal_gland hypothalamus |
| gptkbp:dysregulationAssociatedWith |
gptkb:depression
gptkb:Cushing's_syndrome Addison's disease anxiety disorders |
| gptkbp:feedback_mechanism |
negative feedback by cortisol
|
| gptkbp:firstDescribed |
mid-20th century
|
| gptkbp:function |
regulation of metabolism
regulation of mood regulation of digestion regulation of energy storage regulation of immune system regulation of stress response |
| gptkbp:hormone_released |
gptkb:corticotropin-releasing_hormone
gptkb:adrenocorticotropic_hormone cortisol |
| https://www.w3.org/2000/01/rdf-schema#label |
Hypothalamic–pituitary–adrenal axis
|
| gptkbp:location |
vertebrates
|
| gptkbp:regulates |
circadian rhythm
|
| gptkbp:relatedTo |
gptkb:hypothalamic–pituitary–gonadal_axis
gptkb:hypothalamic–pituitary–thyroid_axis |
| gptkbp:studiedBy |
endocrinology
|
| gptkbp:bfsParent |
gptkb:HPA
|
| gptkbp:bfsLayer |
6
|