Human carbonic anhydrase II

URI: https://gptkb.org/entity/Human_carbonic_anhydrase_II
GPTKB entity
Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:CA_II
gptkb:carbonate_dehydratase_II
carbonic anhydrase B
gptkbp:associatedWith gptkb:osteopetrosis
renal tubular acidosis
gptkbp:cofactor zinc
gptkbp:discoveredBy 1932
gptkbp:EC_number 4.2.1.1
gptkbp:enzymeClassification lyase
gptkbp:family gptkb:carbonic_anhydrase_family
gptkbp:function catalyzes the reversible hydration of carbon dioxide
gptkbp:gene gptkb:CA2
https://www.w3.org/2000/01/rdf-schema#label Human carbonic anhydrase II
gptkbp:inhibitedBy gptkb:acetazolamide
gptkb:brinzolamide
gptkb:methazolamide
gptkb:dorzolamide
gptkbp:locatedOnChromosome 8
8q21.2
gptkbp:location gptkb:cytoplasm
gptkbp:molecularWeight 29 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB gptkb:1CA2
gptkbp:product gptkb:proton
bicarbonate
gptkbp:structure monomer
gptkbp:substrate gptkb:water
carbon dioxide
gptkbp:tissue_specificity gptkb:kidney
gptkb:osteoclasts
gastrointestinal tract
erythrocytes
gptkbp:UniProtID P00918
gptkbp:bfsParent gptkb:1U7V
gptkbp:bfsLayer 7