|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:associatedWith
|
carbonic anhydrase II deficiency syndrome
|
|
gptkbp:cofactor
|
zinc ion
|
|
gptkbp:discoveredBy
|
1932
|
|
gptkbp:EC_number
|
4.2.1.1
|
|
gptkbp:enzyme
|
carbonic anhydrase IX
carbonic anhydrase XII
carbonic anhydrase I
carbonic anhydrase III
carbonic anhydrase IV
|
|
gptkbp:fullName
|
gptkb:Carbonic_anhydrase_II
|
|
gptkbp:function
|
catalyzes the reversible hydration of carbon dioxide
|
|
gptkbp:gene
|
gptkb:CA2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CA II
|
|
gptkbp:inhibitedBy
|
gptkb:acetazolamide
gptkb:brinzolamide
gptkb:methazolamide
gptkb:dorzolamide
sulfonamides
|
|
gptkbp:locatedOnChromosome
|
chromosome 8q22
|
|
gptkbp:location
|
gptkb:cytoplasm
|
|
gptkbp:medicalUse
|
target for anticonvulsants
target for diuretics
target for glaucoma drugs
|
|
gptkbp:molecularWeight
|
29 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:osteopetrosis
renal tubular acidosis
cerebral calcification
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1CA2
|
|
gptkbp:structure
|
monomeric protein
|
|
gptkbp:tissue_specificity
|
gptkb:kidney
eye
gastrointestinal tract
erythrocytes
|
|
gptkbp:UniProtID
|
P00918
|
|
gptkbp:bfsParent
|
gptkb:Carbonic_anhydrase_2
|
|
gptkbp:bfsLayer
|
7
|