Human African trypanosomiasis

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects blood
humans
central nervous system
lymphatic system
gptkbp:alsoKnownAs gptkb:sleeping_sickness
gptkbp:animalReservoir gptkb:livestock
wild animals
gptkbp:causativeAgent gptkb:Trypanosoma_brucei_gambiense
gptkb:Trypanosoma_brucei_rhodesiense
gptkbp:causedBy gptkb:Trypanosoma_brucei
gptkbp:controls WHO control initiatives
gptkbp:diagnosedBy lumbar puncture
blood smear
gptkbp:endemicTo gptkb:sub-Saharan_Africa
gptkbp:fatalIfUntreated true
gptkbp:firstDescribed 1901
gptkbp:hasEpidemiology mainly rural areas
https://www.w3.org/2000/01/rdf-schema#label Human African trypanosomiasis
gptkbp:incubationPeriod 1 to 3 weeks
gptkbp:mortalityRate high if untreated
gptkbp:notableOutbreaks gptkb:Angola
gptkb:Democratic_Republic_of_the_Congo
gptkb:Uganda
gptkbp:prevention gptkb:entomologist
personal protective equipment
vector control
gptkbp:publicHealthConcern significant in endemic regions
gptkbp:stage2 meningoencephalitic phase
gptkbp:stageName hemolymphatic phase
gptkbp:symptom confusion
fever
headache
sleep disturbances
joint pain
itching
neurological problems
gptkbp:transmittedBy gptkb:tsetse_fly
gptkbp:treatment gptkb:eflornithine
gptkb:melarsoprol
gptkb:pentamidine
suramin
nifurtimox-eflornithine combination therapy
gptkbp:vectorFor gptkb:Glossina_morsitans
gptkb:Glossina_palpalis
gptkbp:WHOStatus neglected tropical disease
gptkbp:zoonotic true
gptkbp:bfsParent gptkb:African_sleeping_sickness
gptkb:Trypanosoma_brucei_rhodesiense
gptkbp:bfsLayer 7