Statements (32)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:chemical_compound
                                        
                                         gptkb:drug  | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         1990  | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            P01CX03
                                        
                                        
                                         | 
                            
| gptkbp:brand | 
                                    
                                        
                                            gptkb:Ornidyl
                                        
                                         gptkb:Vaniqa  | 
                            
| gptkbp:CASNumber | 
                                    
                                        
                                            
                                            66389-74-0
                                        
                                        
                                         | 
                            
| gptkbp:chemicalFormula | 
                                    
                                        
                                            
                                            C12H19F3N2O2
                                        
                                        
                                         | 
                            
| gptkbp:developedBy | 
                                    
                                        
                                            
                                            cancer treatment (not effective)
                                        
                                        
                                         | 
                            
| gptkbp:discoveredBy | 
                                    
                                        
                                            gptkb:Cyrus_Bacchi
                                        
                                         | 
                            
| gptkbp:eliminationHalfLife | 
                                    
                                        
                                            
                                            3 hours (IV)
                                        
                                        
                                         | 
                            
| gptkbp:excretion | 
                                    
                                        
                                            
                                            urine
                                        
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            ornithine decarboxylase inhibitor
                                        
                                        
                                         | 
                            
| gptkbp:meltingPoint | 
                                    
                                        
                                            
                                            ~150°C
                                        
                                        
                                         | 
                            
| gptkbp:metabolism | 
                                    
                                        
                                            
                                            minimal
                                        
                                        
                                         | 
                            
| gptkbp:molecularWeight | 
                                    
                                        
                                            
                                            296.29 g/mol
                                        
                                        
                                         | 
                            
| gptkbp:otherName | 
                                    
                                        
                                            gptkb:DFMO
                                        
                                         gptkb:difluoromethylornithine  | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            topical
                                        
                                        
                                         intravenous  | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            gptkb:anemia
                                        
                                         diarrhea hearing loss seizures  | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            
                                            treatment of African trypanosomiasis
                                        
                                        
                                         treatment of facial hirsutism  | 
                            
| gptkbp:WHOModelListOfEssentialMedicines | 
                                    
                                        
                                            
                                            yes
                                        
                                        
                                         | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Trypanosomiasis
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            6
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            eflornithine
                                        
                                        
                                         |