|
gptkbp:instanceOf
|
gptkb:chemical_compound
antiprotozoal drug
|
|
gptkbp:approvedBy
|
1940s
|
|
gptkbp:ATCCode
|
P01CX01
|
|
gptkbp:CASNumber
|
100-33-4
|
|
gptkbp:category
|
gptkb:antibiotic
antineoplastic agent
antifungal agent
|
|
gptkbp:chemicalFormula
|
C19H24N4O2
|
|
gptkbp:contraindication
|
hypersensitivity to pentamidine
|
|
gptkbp:discoveredBy
|
1938
|
|
gptkbp:eliminationHalfLife
|
5–11 hours
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pentamidine
|
|
gptkbp:IUPACName
|
4,4'-(pentane-1,5-diylbis(oxy))dibenzenecarboximidamide
|
|
gptkbp:KEGGID
|
D00438
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:meltingPoint
|
174–177 °C
|
|
gptkbp:MeSH_ID
|
D010414
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
340.43 g/mol
|
|
gptkbp:origin
|
synthesized
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
4735
CHEMBL1433
DB00738
|
|
gptkbp:routeOfAdministration
|
intramuscular
inhalation
intravenous
|
|
gptkbp:sideEffect
|
gptkb:hypoglycemia
pancreatitis
nephrotoxicity
hypotension
hyperglycemia
|
|
gptkbp:synonym
|
gptkb:pentamidine_isethionate
gptkb:pentamidine_methanesulfonate
|
|
gptkbp:UNII
|
R7T0YL8B0G
|
|
gptkbp:usedFor
|
gptkb:African_trypanosomiasis
gptkb:Pneumocystis_pneumonia
leishmaniasis
|
|
gptkbp:bfsParent
|
gptkb:Pneumocystis_pneumonia
gptkb:Trypanosomiasis
|
|
gptkbp:bfsLayer
|
5
|