melarsoprol

GPTKB entity

Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:drug
organic arsenical compound
gptkbp:administeredBy intravenous injection
gptkbp:ATCCode P01CD01
gptkbp:CASNumber 494-79-1
gptkbp:chemicalFormula C12H15AsN6OS2
gptkbp:contraindication hypersensitivity to arsenic compounds
gptkbp:developedBy gptkb:Aventis
gptkbp:discoveredIn 1949
https://www.w3.org/2000/01/rdf-schema#label melarsoprol
gptkbp:isA antineoplastic agent
arsenic-containing drug
gptkbp:KEGGID D02368
gptkbp:legalStatus prescription only
gptkbp:MeSH_ID D008557
gptkbp:molecularWeight 398.34 g/mol
gptkbp:origin synthesized from dimercaprol and melarsen oxide
gptkbp:otherName gptkb:Mel_B
arsobal
gptkbp:PubChem_CID 4057
6706
gptkbp:riskFactor high toxicity
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect gptkb:encephalopathy
fever
vomiting
hypertension
rash
polyneuropathy
gptkbp:UNII 8U6A1WP42K
gptkbp:usedFor treatment of African trypanosomiasis
treatment of sleeping sickness
gptkbp:usedIn late-stage Trypanosoma brucei infection
gptkbp:bfsParent gptkb:Trypanosomiasis
gptkbp:bfsLayer 5