Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
chaperonin |
| gptkbp:alternativeName |
Chaperonin 60
Heat shock protein 60 |
| gptkbp:cofactor |
gptkb:ATP
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
HSPD1 gene
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:function |
protein folding
prevention of protein aggregation |
| https://www.w3.org/2000/01/rdf-schema#label |
Hsp60
|
| gptkbp:inducedBy |
heat shock
cellular stress |
| gptkbp:locatedOnChromosome |
chromosome 2q33.1
|
| gptkbp:molecularWeight |
~60 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
gptkb:Bacteria |
| gptkbp:orthologIn |
GroEL
|
| gptkbp:partner |
Hsp10
|
| gptkbp:PDB |
4PJ1
|
| gptkbp:postTranslationalModification |
phosphorylation
acetylation |
| gptkbp:role |
cellular stress response
mitochondrial protein import |
| gptkbp:significance |
gptkb:cancer
neurodegenerative diseases autoimmune diseases |
| gptkbp:structure |
tetradecamer
|
| gptkbp:subcellularLocation |
mitochondrial matrix
|
| gptkbp:UniProtID |
P10809
|
| gptkbp:bfsParent |
gptkb:Heat_shock_protein
|
| gptkbp:bfsLayer |
6
|