Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:clusters_in_mammals |
HoxA
HoxB HoxC HoxD |
| gptkbp:colinearity |
spatial and temporal
|
| gptkbp:conservedIn |
bilaterian animals
|
| gptkbp:contains |
gptkb:Hox_genes
homeobox domain conserved sequence motif |
| gptkbp:controls |
segment identity
|
| gptkbp:discoveredBy |
gptkb:Drosophila_melanogaster
|
| gptkbp:encodes |
DNA-binding proteins
|
| gptkbp:evolutionary_origin |
gene duplication
|
| gptkbp:expressed_during |
embryonic development
|
| gptkbp:expressedIn |
spatially restricted domains
|
| gptkbp:expression_pattern |
colinear with chromosomal arrangement
|
| gptkbp:firstDescribed |
gptkb:Edward_B._Lewis
|
| gptkbp:foundIn |
animals
|
| gptkbp:function |
body plan specification
|
| gptkbp:homologous_to |
homeobox genes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hox gene complex
|
| gptkbp:influenced |
craniofacial development
limb development vertebral identity |
| gptkbp:involves |
morphogenesis
organogenesis |
| gptkbp:locatedOn |
chromosomes
|
| gptkbp:mutationAssociatedWith |
homeotic transformation
|
| gptkbp:mutations_associated_with |
developmental disorders
|
| gptkbp:number_of_clusters_in_mammals |
four
|
| gptkbp:organized_as |
clusters on chromosomes
|
| gptkbp:orthologIn |
humans
mice fruit flies |
| gptkbp:presentIn |
invertebrates
vertebrates |
| gptkbp:regulates |
gene expression
anterior-posterior axis development |
| gptkbp:relatedTo |
NK gene cluster
ParaHox gene cluster |
| gptkbp:requires |
proper body segmentation
|
| gptkbp:studiedBy |
evolutionary biology
genetics molecular biology evolutionary developmental biology |
| gptkbp:studies |
knockout mice
transgenic animals |
| gptkbp:transcription_factor |
yes
|
| gptkbp:bfsParent |
gptkb:Antennapedia
|
| gptkbp:bfsLayer |
6
|