Statements (96)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:conservedIn |
bilaterian animals
|
| gptkbp:contains |
gptkb:Hox_genes
homeobox domain |
| gptkbp:discoveredBy |
gptkb:Drosophila_melanogaster
|
| gptkbp:encodes |
transcription factors
|
| gptkbp:evolutionary_origin |
gene duplication
|
| gptkbp:expressed_during |
embryonic development
|
| gptkbp:firstDescribed |
gptkb:Edward_B._Lewis
|
| gptkbp:foundIn |
animals
|
| gptkbp:function |
body plan specification
|
| gptkbp:genes_arranged |
colinearly
|
| gptkbp:homologous_to |
homeotic gene clusters in Drosophila
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hox gene clusters
|
| gptkbp:influenced |
eye development
organogenesis craniofacial development kidney development nervous system development segment identity heart development bone development lung development urogenital system development immune system development hair follicle development limb development cartilage development neural crest development spinal cord patterning blood vessel development somite formation pancreas development tooth development prostate development gut development testis development mammary gland development lymphatic vessel development ear development thyroid development reproductive tract development vertebral identity pituitary development liver development thymus development digit formation musculoskeletal development hindbrain segmentation ovary development adrenal gland development anal canal development bladder development cloaca development colon development endocrine system development esophagus development external genitalia development genital tubercle development intestine development larynx development ligament development muscle patterning nose development parathyroid development pharyngeal arch development rectum development rib formation sensory organ development skin appendage development spleen development stomach development tail development tendon development tongue development trachea development urethra development |
| gptkbp:locatedOn |
different chromosomes in mammals
|
| gptkbp:mutationAssociatedWith |
homeotic transformations
|
| gptkbp:names_of_clusters_in_mammals |
HoxA
HoxB HoxC HoxD |
| gptkbp:notableAbsence |
sponges
cnidarians |
| gptkbp:number_of_clusters_in_mammals |
four
|
| gptkbp:presentIn |
invertebrates
vertebrates |
| gptkbp:regulates |
anterior-posterior axis development
|
| gptkbp:relatedTo |
NK gene clusters
ParaHox gene clusters |
| gptkbp:studiedBy |
evolutionary developmental biology
|
| gptkbp:studies |
knockout mice
|
| gptkbp:bfsParent |
gptkb:Polycomb_Repressive_Complex_1
gptkb:Polycomb_Repressive_Complex_2 |
| gptkbp:bfsLayer |
8
|